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Warner E, Messersmith H, Causer P, Eisen A, Shumak R, Plewes D. Systematic review: using magnetic resonance imaging to screen women at high risk for breast cancer. Ann Intern Med. 2008;148(9):671–9. On the sustainability front, hibiscus plants are relatively hardy and can thrive in a variety of climatic conditions, making them a suitable choice for sustainable agriculture. They often require less water and fewer pesticides compared to other cash crops, contributing to a more sustainable and environmentally friendly farming practice. One study in rats found that adding ground hibiscus to animal feed reduced body weight, body fat, and pro-inflammatory compounds in fat tissue ( 18). Other studies have found that hibiscus extracts may be as effective as pharmaceutical medications for high blood pressure. However, more research is needed ( 14, 15). Obesity Natural health products (NHPs) are materials isolated from various food and plant sources that have been shown to have medicinal properties [ 16]. The commonly used chemotherapeutic taxol was isolated from the bark extract of the Pacific yew tree, Taxus brevifolia, when the extract was shown to have a cytotoxic effect [ 17]. Although many treatments have been derived from natural sources, we have yet to exhaust nature’s vast variety of selection. It is possible that a well-tolerated, highly potent anticancer compound is still left to be discovered and developed into a novel cancer therapeutic. Indeed, many NHPs have been shown to induce apoptosis selectively in cancer cells, including our research into dandelion root, lemongrass, and long pepper extracts [ 18, 19, 20]. Traditionally, NHPs have been used widely as both medicinal and food products [ 21].
Having grown up with hibiscus flowers, usually bight red with the long pistil reaching for the sun with yellow covered stamens prominently displayed and so familiar, I was captivated when I first found hibiscus seed oil from one of my suppliers. The comedogenicity of hibiscus oil isn't well studied. Given the fatty acid profile and how well it's balanced, you would expect it to fall in the 1-2 range on the comedogenicity scale. It is a light oil that wouldn't be expected to clog pores, but the higher oleic acid levels make it best for dry skin types. Applying hibiscus oil on a daily basis might help eliminate weak and brittle hair. Its abundant vitamin, mineral, and protein content fortifies the hair shafts, minimising split ends, and averting breakage. Your hair can more successfully tolerate style, heat, and environmental stressors when it is stronger. 3. Conditions your hair It's rich in antioxidants, vitamins, and fatty acids, which provide numerous benefits for skin and hair health. Still, studies in humans are necessary to better understand the potential anti-obesity effects of hibiscus. Metabolic syndromeIt doesn't make my hair look oily, because I wash it out with a shampoo made for extra dry hair. The shampoo is designed to leave moisture in the hair, so I don't have to worry about the oil getting stripped away. Hibiscus farming and oil production present unique opportunities for humanitarian and sustainability initiatives, although the impact can vary depending on regional practices and scales of operation. From a humanitarian perspective, hibiscus cultivation can empower local communities, especially in developing countries.
A 2022 review found that hibiscus tea could reduce levels of LDL cholesterol more effectively than other types of tea or a placebo ( 12). Especially during the winter, my skin gets really dry and tight. A warm bath containing hibiscus oil moisturizes my skin and makes it more supple. Whole cell ROS generation was monitored with the small molecule 2′, 7′-dicholorofluorescin diacetate (H 2DCFDA). H 2DCFDA enters the cell and is deacetylated by esterases and oxidized by ROS to the highly fluorescent 2′, 7′-dicholorofluorescein (DCF) (excitation 495 nm; emission 529 nm). This protocol is similar to that previously published [ 18, 19]. Cells were pretreated with 20 μM H 2DCFDA (Sigma-Aldrich Canada, Cat. No. D6883, Mississauga, ON, Canada) for 30 min at 37 °C protected from light at 5% CO 2. Cells were treated for the indicated durations, collected, centrifuged at 3500×g for 5 min, and resuspended in PBS. Percentage of DCF positive cells was quantified using the Tali Image-Based Cytometer (Life Technologies Inc., Burlington, ON, CA, Cat No. T10796) using 13 random fields per group with the green channel (excitation 458 nm; emission 525/20 nm). Cells were monitored with microscopy and counterstained with Hoechst 33342. Images were taken with a Leica DMI6000 fluorescent microscope (Wetzlar, Germany) at 400x magnification using LAS AF6000 software. Mitochondrial potential monitoring Hibiscus oil is great for the hair and scalp. There is some thought that it may stimulate hair growth and could function as a natural alternative to medicated options for some people trying to regrow hair. Hibiscus hair oil is lovely, light, and non-greasy. Several human trials have found that hibiscus beverages and supplements can decrease blood pressure ( 11, 12).
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Ochani PC, D'Mello P. Antioxidant and antihyperlipidemic activity of Hibiscus sabdariffa Linn. Leaves and calyces extracts in rats. Indian J Exp Biol. 2009;47(4):276–82. You can apply hibiscus oil directly to your hair and scalp as a leave-in treatment or add it to your regular hair products. Massage the oil into your scalp and hair, focusing on the ends, and leave it in for at least an hour or overnight before washing it out. 6. Can I use fresh hibiscus flowers to make oil?
Tetramethylrhodamine methyl ester (TMRM) (Gibco BRL, VWR, Mississauga, ON, CA, Cat No. 89139–392) was used for detecting mitochondrial membrane potential (MMP), an indicator of healthy intact mitochondria. This protocol is similar to that previously published [ 18, 19]. Following incubation with TMRM, cells were collected, washed with 1x PBS, resuspended in PBS, and then analyzed using the Tali Image-Based Cytometer (Life Technologies Inc., Burlington, ON, CA, Cat No. T10796). Cells from 13 random fields were analyzed using the red (ex. 530 nm; em. 585 nm) channel. Cells were monitored with microscopy and counterstained with Hoechst 33342. Images were taken with a Leica DMI6000 fluorescent microscope (Wetzlar, Germany) at 400x magnification using LAS AF6000 software. Statistical analysis Step 3: Stir the mixture well for a few minutes while it’s warm. Once the oil is blended well, keep it aside to cool down. We specialize in scientifically-formulated oil serums, merging traditional wisdom with modern data to create oils for every skin type and concern. Anders C, Carey LA. Understanding and treating triple-negative breast cancer. Oncology (Williston Park). 2008;22(11):1233–9 discussion 1239–40, 1243.The extract from hibiscus flowers is a powerhouse of bioactive compounds, many of which have potential benefits for the skin and hair. This is often sold in the powdered form. Hibiscus flower powder contains many phytochemicals with skin benefits. Among the most notable are the astringent tannins, which can help tighten pores and control excess oil on the skin. The extract is also rich in specific phenolic acids like protocatechuic acid, a potent antioxidant that has shown anti-inflammatory and antimicrobial properties. These phenolic acids can be beneficial for a variety of skin issues, including acne, signs of aging, and uneven skin tone. To withdraw the extract, strain the oil. Make sure there’s no flower debris. Here’s a 4-step guide: The mechanism of apoptosis induction in breast cancer is a topic of great interest to determine the underlying cause of cell death. Previously, we have shown that ethanolic extracts of lemongrass and aqueous extracts of dandelion root were able to induce oxidative stress and decrease mitochondrial membrane potential, leading to apoptosis induction in cancer cells [ 18, 19]. While the exact mechanism is not yet clear, it has been hypothesized that high ROS levels can activate cellular stress mechanisms and may sensitize cancer cells to further ROS production leading to apoptosis [ 9]. Indeed, our results indicate that HE treatment led to increased ROS generation in both triple-negative and ER+ breast cancer cells (Fig. 5). Moreover, taxol and cisplatin treatments in combination with HE showed increased ROS generation when compared to individual treatments. This helps explain the increase in apoptosis induction of combination treatments compared to individual treatments as discussed above (Figs. 3, 4). It should be noted that triple-negative breast cancer cells were more vulnerable to oxidative stress than ER-positive breast cancer cells. These are two different cells with varied susceptibilities, and the lowered ROS generation of ER-positive breast cancer treatment indicates either an alternate mechanism of apoptosis induction or a need for increased dosage. Further, we have demonstrated that HE combination treatment is able to enhance the mitochondrial membrane potential reduction in breast cancer cells (Fig. 6). Hibiscus oil has made its way onto the bareLUXE list of luxurious carrier oils for several reasons. This delicate, light, and subtly scented carrier oil is special because of the skin benefits you'll experience when using it, but also because it is romantic and rarer than a lot of other carrier oils used in natural skincare products.
A common hesitation of using natural health product extracts alongside chemotherapies is the possibility of negative drug interactions, leading to reduced efficacy in treatment. Our goal was to investigate whether or not combination HE treatments would inhibit, not affect, or enhance the efficacy of chemotherapeutic treatments. Indeed, we found that taxol and cisplatin treatments on triple-negative breast cancer cells were enhanced with the addition of 1 mg/mL (sublethal dosage in individual treatment) HE treatment (Fig. 2) while unaffected in ER-positive breast cancer cells. These results clearly indicate that HE’s interaction with chemotherapeutic drugs is positive or has no interaction in breast cancer cells. If any effect was observed at all, HE treatment enhanced the efficacy of chemotherapeutic treatments. Moreover, HE combination treatments on NHF cells were able to reduce the toxicity of taxol (Fig. 4a). Extent of apoptosis induced by 0.01 μM taxol in combination with HE was equivalent to that induced by 0.5 μM taxol alone (Fig. 2a). This 50-fold decrease in effective chemotherapy concentration clearly indicates the possibility of reducing chemotherapeutic dosage to avoid adverse side-effects without sacrificing efficacy. As such, HE could serve a significant purpose in terms of adjuvant therapy.https://img-static.popxo.com/tr:w-600,rt-auto,c-at_max/app_photos/images/2386/original/hair-oil-hibiscus-hair-fall-DIY-hair-mask-recipes_%283%29.jpg Hibiscus oil is a very beneficial oil to be used on, cuts, bruises, and wounds. It helps to cure them in no time and does not harm skin in any way and has no side-effects if applied on bruises or cuts directly. Hibiscus Oil is made from the Hibiscus plant's flowers. Hibiscus flowers have been used for their medicinal properties since ancient times. It contains vitamin A, vitamin C, amino acids, alpha-hydroxy acids, and powerful antioxidants that prove beneficial for both skin and hair. However, no human studies have looked at the antibacterial effects of hibiscus tea, so it is still unclear how these results may translate to humans. Summary
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