Green coffee bean extract. Green coffee bean extract comes from raw coffee beans that haven’t been roasted. These beans contain chlorogenic acid, which could significantly decrease body weight without severe adverse effects, a 2019 study published in Nutrients found. However, the study focused on daily consumption of at least 300 mg of chlorogenic acid over the course of 12 weeks, and was not administered via patch. In other words, the results aren’t necessarily comparable. And if you're considering trying chlorogenic acid in another form, always, always talk to your doctor first. DeFina LF, et al. (2011). Effects of omega-3 supplementation in combination with diet and exercise on weight loss and body composition. DOI: Shekelle P, et al. (2003). Ephedra and ephedrine for weight loss and athletic performance enhancement: Clinical efficacy and side effects: Summary. AHRQ evidence report summaries. An article in the British Journal of Pharmacology explains how manufacturers of transdermal patches face several challenges when developing their products.

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A safe and sustainable rate of weight loss is about 1–2 lb per week. Once the person reaches their initial goal, they may continue to try to lose weight, if they wish to or a doctor advises it. Cannabidiol. Cannabidiol, or CBD, has gained significant popularity, particularly as a method for relieving pain and anxiety, and it’s starting to pop up in patch form as well. CBD oil may have some appetite-suppressing qualities, says Dr. Seltzer, which is why people may be intrigued enough to try it. However, like CBD creams, these patches are usually intended for uses like muscle pain relief, and, as with most others on this list, more research is needed when it comes CBD for weight loss.

Onakpoya I, et al. (2011). The use of green coffee extract as a weight loss supplement: A systematic review and meta-analysis of randomised clinical trials. DOI: Known by the scientific name mentha canadensis, Japanese mint is found, yes, in Japan, as well and other Asian countries such as China and Java—but it’s also found all over North America, where it’s called Canada mint or American mint. So, basically, this is a very common, very international variety of mint. Does it have any special qualities? https://www.ema.europa.eu/en/documents/herbal-report/draft-assessment-report-fucus-vesiculosus-l-thallus_en.pdf If a person is likely to experience health benefits by losing weight, a doctor may recommend that they aim to reduce their starting weight by 10%. For example, a person with a weight of 200 pounds (lb) could try to lose 20 lb.

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Researchers have studied the effects of both green tea and green tea extract on weight loss. Drinking green tea supposedly increases the body’s metabolic rate, breaks down fat cells, and decreases the amount of fat that the body produces. Green coffee bean extract also contains caffeine, which, research has shown, may help with weight loss. So, sounds kinda promising? Side effectsKorukanti, V. P., et al. (2013). Evaluation of antiobesity activity of Fucus vesiculosus [Abstract]. Popular brands, like the Thrive weight loss patch, use green coffee bean extract, which comes from raw, unroasted coffee beans. It contains a substance called chlorogenic acid, which has shown to possibly prevent weight gain (in mice, though). Bitter orange extract. Bitter orange extract is found in citrus fruits such as Seville oranges and contains synephrine, a stimulant with effects similar to ephedrine, according to a 2012 study. Because of this, makers of bitter orange extract patches have claimed it can help with weight loss by helping to burn more calories and fat, as well as by suppressing appetite. However, the study concluded that these effects are minimal and further research is still needed.

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Doctors recommend following a low calorie diet to aid weight loss. The number of calories that a person should consume every day depends on several factors, including their baseline weight, gender, age, and activity level. A doctor or nutritionist can help a person calculate the best total daily calorie intake and macronutrient breakdown for them. Skin patches (also called transdermal patches) aren’t new. They’ve long been used to treat a range of health conditions. However, there are a few reasons to be skeptical of weight loss patches: One of the benefits of using a patch is avoiding the need for the medicine to pass through the digestive tract. If the digestive system metabolizes an ingredient before the blood absorbs it, it may lose its effectiveness.

Jorge Moreno, MD, is an internal medicine physician and obesity medicine specialist at Yale Medicine. Many substances that claim to promote fat loss aren’t that helpful — and they can even be dangerous.